The introduction of the Nile Perch (Lates niloticus) into Lake Victoria has led to significant ecological ramifications, particularly concerning the region’s rich cichlid diversity. This invasive predator, introduced in the 1950s for commercial fishing purposes, has since proliferated rapidly, outcompeting native species for resources and disrupting the delicate ecological balance of the lake. The Nile Perch’s voracious appetite and rapid growth have enabled it to dominate the lake’s food web, leading to the decline and even extinction of numerous cichlid species. With an estimated 250 cichlid species once thriving in Lake Victoria, many have faced population declines or local extinctions due to predation pressure from the Nile Perch. Consequently, this invasion has not only altered the structure and function of the lake’s ecosystem but also jeopardized the livelihoods of local communities dependent on fisheries resources. Efforts to mitigate the impact of the Nile Perch invasion include the promotion of sustainable fishing practices and the implementation of conservation measures to protect remaining cichlid populations and restore ecological balance in Lake Victoria.